PT-141 (Bremelanotide) is a synthetic cyclic heptapeptide analog of α-MSH that acts as a non-selective agonist of the melanocortin receptors, with primary activity at MC4R and MC3R in the central nervous system. Unlike PDE5 inhibitors (sildenafil, tadalafil) that work vascularly, PT-141 acts directly on the hypothalamic circuits that drive sexual desire and arousal — a fundamentally different mechanism.
It is one of the most extensively studied peptides for hypoactive sexual desire disorder (HSDD), erectile response, and female sexual arousal disorder, with published data in both preclinical and clinical research. Onset in reported studies is rapid (minutes to a couple of hours), and effects are independent of visual or tactile stimulation because the signal originates centrally.
BioPeptideX supplies PT-141 as a 10 mg lyophilized powder, ≥99% HPLC verified, sealed under inert atmosphere and shipped with a Certificate of Analysis. Every vial is lot-traceable — for laboratory research use only.