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Research guide · Anti-Aging & Longevity

Epithalon — research protocol

Epithalon (Epitalon) — synthetic tetrapeptide (Ala-Glu-Asp-Gly) derived from the pineal gland peptide Epithalamin. Studied for telomerase activation, telomere elongation, circadian rhythm restoration and longevity research. Lyophilized powder, 99% HPLC purity.

Evidence boundary

This guide summarizes study areas and sources associated with the compound. BioPeptideX does not convert experimental information into a clinical regimen or recommend an individual dose, frequency, route or duration.

Catalog presentations

40mg

Concentration table

Mathematical reference only; this is not a dosing recommendation.

Resulting concentration20.00 mg/mL
On a U-100 syringe · 1 unit contains0.200 mg

Research areas

  • The gold-standard longevity peptide — telomerase activator
  • Studied for telomere elongation and cellular aging reversal
  • Restores melatonin rhythm and deep restorative sleep
  • Modulates the pineal–hypothalamic–pituitary axis
  • Investigated in geroprotection and lifespan-extension research
  • Lyophilized powder, 99% HPLC verified purity — COA included

Most-cited research protocols

Educational information based on research protocols and literature; it does not replace guidance from a healthcare professional.

Epitalon, also known as epithalon (AEDG), is a small four-amino-acid peptide primarily studied for its role in aging, particularly concerning telomeres and the body's sleep/melatonin rhythm. This page outlines reported dosing contexts, mixing instructions, supplies, and safety considerations.

DoseFrequencyDurationRoute
Standard short cycle5 mg/dayevening20 daysSubQ
Condensed cycle10 mg/dayevening10 daysSubQ

Cycle: 2-3 times per year, with cycles spaced 4-6 months apart. Each cycle delivers roughly 100 mg total.

Benefits and research observations: Dosing is often in the evening to align with natural melatonin rhythms. Monitor for injection-site reactions, mild drowsiness, and occasional headache or temporary sleep changes as the cycle begins.

Handling and storage

Store unreconstituted product according to its label and maintain the cold chain where applicable. After any preparation, follow only validated instructions for the specific product and diluent. Do not use if packaging is damaged or the solution shows particles or unexpected changes.

Warnings

Do not use this page for self-diagnosis or self-medication. Pregnancy, breastfeeding, minors, cancer history, allergies, active disease and concurrent treatments require individual professional evaluation.

Published sources

  1. 1.Khavinson VK, et al. Bull Exp Biol Med, 2003.
  2. 2.Anisimov VN, et al. Neuro Endocrinol Lett, 2003.
  3. 3.Korkushko OV, et al. Bull Exp Biol Med, 2011.