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Research guide · Cognitive & Focus

Semax — research protocol

Heptapeptide studied for neuroprotective and cognitive enhancement studies.

Evidence boundary

This guide summarizes study areas and sources associated with the compound. BioPeptideX does not convert experimental information into a clinical regimen or recommend an individual dose, frequency, route or duration.

Catalog presentations

5mg10mg15mg

Concentration table

Mathematical reference only; this is not a dosing recommendation.

Resulting concentration2.50 mg/mL
On a U-100 syringe · 1 unit contains0.025 mg

Research areas

  • Heptapeptide ACTH-fragment
  • BDNF compound
  • Sealed sterile vial

Most-cited research protocols

Educational information based on research protocols and literature; it does not replace guidance from a healthcare professional.

Semax is a synthetic seven-amino-acid peptide derived from ACTH, designed for a longer functional window. It is used in Russian clinical practice for stroke recovery, cognitive disorders, and optic nerve disease, but is not FDA-approved in the US.

DoseFrequencyDurationRoute
Cognitive / nootropic research planningAbout 0.6 to 1.5 mg/daySplit into 2 administrations4-6 weeksIntranasal
Acute ischemic stroke (clinical, Russia)Higher daily amountsMultiple daily administrations10-14 daysIntranasal
Healthy-volunteer cognitive-attention studySingle intranasal administration of about 1.2 mgOne-time research administrationN/AIntranasal
Animal pharmacology (rodent)Up to ~1 mg/kgN/AN/ASubcutaneous

Cycle: Standard short course: 10-14 days. Extended cognitive course: 4-6 weeks. Cycled use: 4-6 weeks on, 2-4 weeks off.

Benefits and research observations: Intranasal effects can be noticed the same day, with patterns of focus and stamina becoming clearer in the first week. Cognitive consistency and neuroprotective signals are described within 2-4 weeks.

Handling and storage

Store unreconstituted product according to its label and maintain the cold chain where applicable. After any preparation, follow only validated instructions for the specific product and diluent. Do not use if packaging is damaged or the solution shows particles or unexpected changes.

Warnings

Do not use this page for self-diagnosis or self-medication. Pregnancy, breastfeeding, minors, cancer history, allergies, active disease and concurrent treatments require individual professional evaluation.

Published sources

  1. 1.Dolotov OV, et al. J Neurochem, 2006.
  2. 2.Ashmarin IP, et al. Patol Fiziol Eksp Ter, 1997.